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Monitoring CSF Proteome Alterations in Amyotrophic Lateral Sclerosis: Obstacles and Perspectives in Translating a Novel Marker Panel to the Clinic

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal disorder of the motor neuron system with poor prognosis and marginal therapeutic options. Current clinical diagnostic criteria are based on electrophysiological examination and exclusion of other ALS-mimicking conditions. Neuroprotective tre...

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Detalles Bibliográficos
Autores principales:	von Neuhoff, Nils, Oumeraci, Tonio, Wolf, Thomas, Kollewe, Katja, Bewerunge, Peter, Neumann, Boris, Brors, Benedikt, Bufler, Johannes, Wurster, Ulrich, Schlegelberger, Brigitte, Dengler, Reinhard, Zapatka, Marc, Petri, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435306/ https://www.ncbi.nlm.nih.gov/pubmed/22970211 http://dx.doi.org/10.1371/journal.pone.0044401

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