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Phototriggerable 2′,7-Caged Paclitaxel

Three different variants of photoactivatable caged paclitaxel (PTX) have been synthesized and their bioactivity was characterized in in vitro assays and in living cells. The caged PTXs contain the photoremovable chromophore 4,5-dimethoxy-2-nitrobenzyloxycarbonyl (Nvoc) attached to position C7, C2�...

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Detalles Bibliográficos
Autores principales: Gropeanu, Radu A., Baumann, Hella, Ritz, Sandra, Mailänder, Volker, Surrey, Thomas, del Campo, Aránzazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435387/
https://www.ncbi.nlm.nih.gov/pubmed/22970137
http://dx.doi.org/10.1371/journal.pone.0043657