Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease

BACKGROUND: Cellular senescence can be a functional barrier to carcinogenesis. We hypothesized that inflammation modulates carcinogenesis through senescence and DNA damage response (DDR). We examined the association between senescence and DDR with macrophage levels in inflammatory bowel disease (IBD...

Descripción completa

Detalles Bibliográficos
Autores principales: Sohn, Jane J., Schetter, Aaron J., Yfantis, Harris G., Ridnour, Lisa A., Horikawa, Izumi, Khan, Mohammed A., Robles, Ana I., Hussain, S. Perwez, Goto, Akiteru, Bowman, Elise D., Hofseth, Lorne J., Bartkova, Jirina, Bartek, Jiri, Wogan, Gerald N., Wink, David A., Harris, Curtis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435404/
https://www.ncbi.nlm.nih.gov/pubmed/22970173
http://dx.doi.org/10.1371/journal.pone.0044156

Ejemplares similares

Ejemplares similares