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Homology Modeling of Dopamine D(2) and D(3) Receptors: Molecular Dynamics Refinement and Docking Evaluation
Dopamine (DA) receptors, a class of G-protein coupled receptors (GPCRs), have been targeted for drug development for the treatment of neurological, psychiatric and ocular disorders. The lack of structural information about GPCRs and their ligand complexes has prompted the development of homology mod...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435408/ https://www.ncbi.nlm.nih.gov/pubmed/22970199 http://dx.doi.org/10.1371/journal.pone.0044316 |