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Maintenance of Acinar Cell Organization is Critical to Preventing Kras-Induced Acinar-Ductal Metaplasia
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers owing to a number of characteristics including difficulty in establishing early diagnosis and the absence of effective therapeutic regimens. A large number of genetic alterations have been ascribed to PDAC with mutations in th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435479/ https://www.ncbi.nlm.nih.gov/pubmed/22665051 http://dx.doi.org/10.1038/onc.2012.210 |