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FUNCTIONAL CHARACTERIZATION OF ABCC2 PROMOTER POLYMORPHISMS AND ALLELE SPECIFIC EXPRESSION

Multidrug resistance protein 2 (MRP2, ABCC2) is an efflux membrane transporter highly expressed in liver, kidney and intestine with important physiological and pharmacological roles. The goal of this study was to investigate the functional significance of promoter region polymorphisms in ABCC2 and p...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tan D., Markova, Svetlana, Liu, Wanqing, Gow, Jason M., Baldwin, R. Michael, Habashian, Mahnoush, Relling, Mary V., Ratain, Mark J., Kroetz, Deanna L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435480/ https://www.ncbi.nlm.nih.gov/pubmed/22664480 http://dx.doi.org/10.1038/tpj.2012.20

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