Roles of Education and IQ in Cognitive Reserve in Parkinson's Disease-Mild Cognitive Impairment

BACKGROUND/AIMS: The role of cognitive reserve in Parkinson's disease (PD)-mild cognitive impairment (MCI) is incompletely understood. METHODS: The relationships between PD-MCI, years of education, and estimated premorbid IQ were examined in 119 consecutive non-demented PD patients using logist...

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Detalles Bibliográficos
Autores principales: Armstrong, M.J., Naglie, G., Duff-Canning, S., Meaney, C., Gill, D., Eslinger, P.J., Zadikoff, C., Mapstone, M., Chou, K.L., Persad, C., Litvan, I., Mast, B.T., Fox, S., Tang-Wai, D.F., Marras, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435526/
https://www.ncbi.nlm.nih.gov/pubmed/22962558
http://dx.doi.org/10.1159/000341782
Descripción
Sumario:BACKGROUND/AIMS: The role of cognitive reserve in Parkinson's disease (PD)-mild cognitive impairment (MCI) is incompletely understood. METHODS: The relationships between PD-MCI, years of education, and estimated premorbid IQ were examined in 119 consecutive non-demented PD patients using logistic regression models. RESULTS: Higher education and IQ were associated with reduced odds of PD-MCI in univariate analysis. In multivariable analysis, a higher IQ was associated with a significantly decreased odds of PD-MCI, but education was not. CONCLUSION: The association of higher IQ and decreased odds of PD-MCI supports a role for cognitive reserve in PD, but further studies are needed to clarify the interaction of IQ and education and the impact of other contributors such as employment and hobbies.

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