In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues

Mutually exclusive cell fate determination of CD4 helper or CD8 killer T cells occurs in the thymus. These T-cell subsets are not believed to redirect other lineages. Here we showed that retinoic acid and transforming growth factor-β1 promoted the differentiation of CD8αα T cells from CD4 T cells in...

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Detalles Bibliográficos
Autores principales: Nambu, Yukiko, Hayashi, Tatsunari, Jang, Kyoung-Jin, Aoki, Koji, Mano, Hiroto, Nakano, Keiko, Osato, Motomi, Takahashi, Katsu, Itoh, Katsuhiko, Teramukai, Satoshi, Komori, Toshihisa, Fujita, Jun, Ito, Yoshiaki, Shimizu, Akira, Sugai, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435563/
https://www.ncbi.nlm.nih.gov/pubmed/22962636
http://dx.doi.org/10.1038/srep00642

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