[1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone

Methyl­ation of [1-hy­droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano­late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine...

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Detalles Bibliográficos
Autores principales: Kloubert, Tobias, Kretschmer, Robert, Görls, Helmar, Westerhausen, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435659/
https://www.ncbi.nlm.nih.gov/pubmed/22969532
http://dx.doi.org/10.1107/S160053681203396X
Descripción
Sumario:Methyl­ation of [1-hy­droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano­late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine unit are twisted [the indolizine ring system makes dihedral angles of 34.67 (7) and 77.49 (5)°, respectively, with the pyridyl and pyridinoyl rings] with single bonds between the central unit and the attached pyridine ring [1.459 (3) Å] and the pyridinoyl group [1.483 (3) Å]. There are no classical hydrogen bonds in the crystal structure.

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