[1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone

Methyl­ation of [1-hy­droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano­late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine...

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Autores principales: Kloubert, Tobias, Kretschmer, Robert, Görls, Helmar, Westerhausen, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435659/
https://www.ncbi.nlm.nih.gov/pubmed/22969532
http://dx.doi.org/10.1107/S160053681203396X
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author Kloubert, Tobias
Kretschmer, Robert
Görls, Helmar
Westerhausen, Matthias
author_facet Kloubert, Tobias
Kretschmer, Robert
Görls, Helmar
Westerhausen, Matthias
author_sort Kloubert, Tobias
collection PubMed
description Methyl­ation of [1-hy­droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano­late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine unit are twisted [the indolizine ring system makes dihedral angles of 34.67 (7) and 77.49 (5)°, respectively, with the pyridyl and pyridinoyl rings] with single bonds between the central unit and the attached pyridine ring [1.459 (3) Å] and the pyridinoyl group [1.483 (3) Å]. There are no classical hydrogen bonds in the crystal structure.
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spelling pubmed-34356592012-09-11 [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone Kloubert, Tobias Kretschmer, Robert Görls, Helmar Westerhausen, Matthias Acta Crystallogr Sect E Struct Rep Online Organic Papers Methyl­ation of [1-hy­droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano­late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine unit are twisted [the indolizine ring system makes dihedral angles of 34.67 (7) and 77.49 (5)°, respectively, with the pyridyl and pyridinoyl rings] with single bonds between the central unit and the attached pyridine ring [1.459 (3) Å] and the pyridinoyl group [1.483 (3) Å]. There are no classical hydrogen bonds in the crystal structure. International Union of Crystallography 2012-08-04 /pmc/articles/PMC3435659/ /pubmed/22969532 http://dx.doi.org/10.1107/S160053681203396X Text en © Kloubert et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Kloubert, Tobias
Kretschmer, Robert
Görls, Helmar
Westerhausen, Matthias
[1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title_full [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title_fullStr [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title_full_unstemmed [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title_short [1-Meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
title_sort [1-meth­oxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435659/
https://www.ncbi.nlm.nih.gov/pubmed/22969532
http://dx.doi.org/10.1107/S160053681203396X
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AT westerhausenmatthias 1methoxy3pyridin2ylindolizin2ylpyridin2ylmethanone

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