N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester

The title compound, C(13)H(15)ClN(2)O(6), was synthesized by hypochlorous acid-mediated chlorination of N-acetyl-3-nitro-l-tyrosine ethyl ester. The OH group forms an intra­molecular O—H⋯O hydrogen bond to the nitro group and the N—H group forms an inter­molecular N—H⋯O hydrogen bonds to an amide O...

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Autores principales: Mutahi, Teresa T., Edagwa, Benson J., Fronczek, Frank R., Uppu, Rao M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435836/
https://www.ncbi.nlm.nih.gov/pubmed/22969682
http://dx.doi.org/10.1107/S1600536812036380
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author Mutahi, Teresa T.
Edagwa, Benson J.
Fronczek, Frank R.
Uppu, Rao M.
author_facet Mutahi, Teresa T.
Edagwa, Benson J.
Fronczek, Frank R.
Uppu, Rao M.
author_sort Mutahi, Teresa T.
collection PubMed
description The title compound, C(13)H(15)ClN(2)O(6), was synthesized by hypochlorous acid-mediated chlorination of N-acetyl-3-nitro-l-tyrosine ethyl ester. The OH group forms an intra­molecular O—H⋯O hydrogen bond to the nitro group and the N—H group forms an inter­molecular N—H⋯O hydrogen bonds to an amide O atom, linking the mol­ecules into chains along [100]. The crystal studied was a non-merohedral twin, with a 0.907 (4):0.093 (4) domain ratio.
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spelling pubmed-34358362012-09-11 N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester Mutahi, Teresa T. Edagwa, Benson J. Fronczek, Frank R. Uppu, Rao M. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(13)H(15)ClN(2)O(6), was synthesized by hypochlorous acid-mediated chlorination of N-acetyl-3-nitro-l-tyrosine ethyl ester. The OH group forms an intra­molecular O—H⋯O hydrogen bond to the nitro group and the N—H group forms an inter­molecular N—H⋯O hydrogen bonds to an amide O atom, linking the mol­ecules into chains along [100]. The crystal studied was a non-merohedral twin, with a 0.907 (4):0.093 (4) domain ratio. International Union of Crystallography 2012-08-31 /pmc/articles/PMC3435836/ /pubmed/22969682 http://dx.doi.org/10.1107/S1600536812036380 Text en © Mutahi et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mutahi, Teresa T.
Edagwa, Benson J.
Fronczek, Frank R.
Uppu, Rao M.
N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title_full N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title_fullStr N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title_full_unstemmed N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title_short N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
title_sort n-acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435836/
https://www.ncbi.nlm.nih.gov/pubmed/22969682
http://dx.doi.org/10.1107/S1600536812036380
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AT uppuraom nacetyl5chloro3nitroltyrosineethylester

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