N-[(2S)-2-Chloro­propano­yl]glycine

The title compound, C(5)H(8)ClNO(3), was prepared by the nucleophilic substitution reaction of (2S)-2-chloro­propanoyl chloride with glycine. The acetate group forms a dihedral angle of 84.6 (1)° with the mean plane of the C—NH—C=O fragment. In the crystal, the molecules are linked by N—H⋯O and O—H⋯...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Hong-shun, Tang, Yi, Li, Yu-long, Xu, Ning, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435838/
https://www.ncbi.nlm.nih.gov/pubmed/22969684
http://dx.doi.org/10.1107/S1600536812036720
_version_ 1782242599078199296
author Sun, Hong-shun
Tang, Yi
Li, Yu-long
Xu, Ning
Xu, Hong
author_facet Sun, Hong-shun
Tang, Yi
Li, Yu-long
Xu, Ning
Xu, Hong
author_sort Sun, Hong-shun
collection PubMed
description The title compound, C(5)H(8)ClNO(3), was prepared by the nucleophilic substitution reaction of (2S)-2-chloro­propanoyl chloride with glycine. The acetate group forms a dihedral angle of 84.6 (1)° with the mean plane of the C—NH—C=O fragment. In the crystal, the molecules are linked by N—H⋯O and O—H⋯O hydrogen bonds, generating a three-dimensional network, which consolidates the crystal packing.
format Online
Article
Text
id pubmed-3435838
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-34358382012-09-11 N-[(2S)-2-Chloro­propano­yl]glycine Sun, Hong-shun Tang, Yi Li, Yu-long Xu, Ning Xu, Hong Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(5)H(8)ClNO(3), was prepared by the nucleophilic substitution reaction of (2S)-2-chloro­propanoyl chloride with glycine. The acetate group forms a dihedral angle of 84.6 (1)° with the mean plane of the C—NH—C=O fragment. In the crystal, the molecules are linked by N—H⋯O and O—H⋯O hydrogen bonds, generating a three-dimensional network, which consolidates the crystal packing. International Union of Crystallography 2012-08-31 /pmc/articles/PMC3435838/ /pubmed/22969684 http://dx.doi.org/10.1107/S1600536812036720 Text en © Sun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sun, Hong-shun
Tang, Yi
Li, Yu-long
Xu, Ning
Xu, Hong
N-[(2S)-2-Chloro­propano­yl]glycine
title N-[(2S)-2-Chloro­propano­yl]glycine
title_full N-[(2S)-2-Chloro­propano­yl]glycine
title_fullStr N-[(2S)-2-Chloro­propano­yl]glycine
title_full_unstemmed N-[(2S)-2-Chloro­propano­yl]glycine
title_short N-[(2S)-2-Chloro­propano­yl]glycine
title_sort n-[(2s)-2-chloro­propano­yl]glycine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435838/
https://www.ncbi.nlm.nih.gov/pubmed/22969684
http://dx.doi.org/10.1107/S1600536812036720
work_keys_str_mv AT sunhongshun n2s2chloropropanoylglycine
AT tangyi n2s2chloropropanoylglycine
AT liyulong n2s2chloropropanoylglycine
AT xuning n2s2chloropropanoylglycine
AT xuhong n2s2chloropropanoylglycine

Ejemplares similares