Cargando…

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

The platelet collagen receptor glycoprotein VI (GPVI) has been suggested to function as a dimer, with increased affinity for collagen. Dissociation constants (K(d)) obtained by measuring recombinant GPVI binding to collagenous substrates showed that GPVI dimers bind with high affinity to tandem GPO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jung, Stephanie M., Moroi, Masaaki, Soejima, Kenji, Nakagaki, Tomohiro, Miura, Yoshiki, Berndt, Michael C., Gardiner, Elizabeth E., Howes, Joanna-Marie, Pugh, Nicholas, Bihan, Dominique, Watson, Steve P., Farndale, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436176/ https://www.ncbi.nlm.nih.gov/pubmed/22773837 http://dx.doi.org/10.1074/jbc.M112.359125

Ejemplares similares

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III
por: Hamaia, Samir W., et al.
Publicado: (2012)

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase
por: Kalamajski, Sebastian, et al.
Publicado: (2016)

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor
por: An, Bo, et al.
Publicado: (2016)

Collagen VI, Conformation of A-domain Arrays and Microfibril Architecture
por: Beecher, Nicola, et al.
Publicado: (2011)

Heterogeneity of Collagen VI Microfibrils: STRUCTURAL ANALYSIS OF NON-COLLAGENOUS REGIONS
por: Maaß, Tobias, et al.
Publicado: (2016)

Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1
por: Jelk, Jennifer, et al.
Publicado: (2013)

Mapping the Effect of Gly Mutations in Collagen on α2β1 Integrin Binding
por: Yigit, Sezin, et al.
Publicado: (2016)

Identification of Neutrophil Granule Glycoproteins as Lewis(x)-containing Ligands Cleared by the Scavenger Receptor C-type Lectin
por: Graham, Sarah A., et al.
Publicado: (2011)

The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion
por: Ridley, Caroline, et al.
Publicado: (2019)

Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury
por: Coulson-Thomas, Vivien J., et al.
Publicado: (2016)

Constitutive Expression of Inter-α-inhibitor (IαI) Family Proteins and Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) by Human Amniotic Membrane Epithelial and Stromal Cells Supporting Formation of the Heavy Chain-Hyaluronan (HC-HA) Complex
por: Zhang, Suzhen, et al.
Publicado: (2012)

Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
por: Kanagawa, Mayumi, et al.
Publicado: (2014)

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
por: Poulter, N. S., et al.
Publicado: (2017)

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3(+) Dendritic Cells and a Subset of Monocytes
por: Huysamen, Cristal, et al.
Publicado: (2008)

The Synthesis of UDP-N-acetylglucosamine Is Essential for Bloodstream Form Trypanosoma brucei in Vitro and in Vivo and UDP-N-acetylglucosamine Starvation Reveals a Hierarchy in Parasite Protein Glycosylation
por: Stokes, Matthew J., et al.
Publicado: (2008)

TSG-6 Regulates Bone Remodeling through Inhibition of Osteoblastogenesis and Osteoclast Activation
por: Mahoney, David J., et al.
Publicado: (2008)

A Mucin-type O-Glycosyltransferase Modulates Cell Adhesion during Drosophila Development
por: Zhang, Liping, et al.
Publicado: (2008)

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation
por: Barthel, Steven R., et al.
Publicado: (2011)

Early Murine T-lymphocyte Activation Is Accompanied by a Switch from N-Glycolyl- to N-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E
por: Redelinghuys, Pierre, et al.
Publicado: (2011)

Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
por: Pedersen, Johannes W., et al.
Publicado: (2011)

Post-assembly Modification of Bordetella bronchiseptica O Polysaccharide by a Novel Periplasmic Enzyme Encoded by wbmE
por: King, Jerry D., et al.
Publicado: (2009)

Interleukin-6 Released from Fibroblasts Is Essential for Up-regulation of Matrix Metalloproteinase-1 Expression by U937 Macrophages in Coculture: CROSS-TALKING BETWEEN FIBROBLASTS AND U937 MACROPHAGES EXPOSED TO HIGH GLUCOSE
por: Sundararaj, Kamala P., et al.
Publicado: (2009)

Loss of α-Dystroglycan Laminin Binding in Epithelium-derived Cancers Is Caused by Silencing of LARGE
por: de Bernabé, Daniel Beltrán-Valero, et al.
Publicado: (2009)

A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus
por: Crispin, Max, et al.
Publicado: (2009)

Rapid Purification and High Sensitivity Analysis of Heparan Sulfate from Cells and Tissues: TOWARD GLYCOMICS PROFILING
por: Guimond, Scott E., et al.
Publicado: (2009)

Trimeric Structure of Langerin
por: Feinberg, Hadar, et al.
Publicado: (2010)

Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion
por: Gopal, Sandeep, et al.
Publicado: (2010)

α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling
por: Kitazume, Shinobu, et al.
Publicado: (2010)

Glycomics Profiling of Chinese Hamster Ovary Cell Glycosylation Mutants Reveals N-Glycans of a Novel Size and Complexity
por: North, Simon J., et al.
Publicado: (2010)

Revised Role of Glycosaminoglycans in TAT Protein Transduction Domain-mediated Cellular Transduction
por: Gump, Jacob M., et al.
Publicado: (2010)

Prolectin, a Glycan-binding Receptor on Dividing B Cells in Germinal Centers
por: Graham, Sarah A., et al.
Publicado: (2009)

In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway
por: Castilho, Alexandra, et al.
Publicado: (2010)

Role of the Netrin-like Domain of Procollagen C-Proteinase Enhancer-1 in the Control of Metalloproteinase Activity
por: Bekhouche, Mourad, et al.
Publicado: (2010)

Identification of Mono- and Disulfated N-Acetyl-lactosaminyl Oligosaccharide Structures as Epitopes Specifically Recognized by Humanized Monoclonal Antibody HMOCC-1 Raised against Ovarian Cancer
por: Shibata, Toshiaki K., et al.
Publicado: (2012)

Monocyte-to-Macrophage Differentiation: SYNTHESIS AND SECRETION OF A COMPLEX EXTRACELLULAR MATRIX
por: Chang, Mary Y., et al.
Publicado: (2012)

Transglutaminase-2 Interaction with Heparin: IDENTIFICATION OF A HEPARIN BINDING SITE THAT REGULATES CELL ADHESION TO FIBRONECTIN-TRANSGLUTAMINASE-2 MATRIX
por: Lortat-Jacob, Hugues, et al.
Publicado: (2012)

Chemical Structure of Trichomonas vaginalis Surface Lipoglycan: A ROLE FOR SHORT GALACTOSE (β1–4/3) N-ACETYLGLUCOSAMINE REPEATS IN HOST CELL INTERACTION
por: Ryan, Christopher M., et al.
Publicado: (2011)

The Streptococcal Binding Site in the Gelatin-binding Domain of Fibronectin Is Consistent with a Non-linear Arrangement of Modules
por: Atkin, Kate E., et al.
Publicado: (2010)

β-N-Acetylhexosaminidases HEXO1 and HEXO3 Are Responsible for the Formation of Paucimannosidic N-Glycans in Arabidopsis thaliana
por: Liebminger, Eva, et al.
Publicado: (2011)

Redefinition of the Carbohydrate Binding Specificity of Helicobacter pylori BabA Adhesin
por: Benktander, John, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_mfmcgumrf0rehk4fjo8fqa81kv