The Antiepileptic Drug Valproic Acid Restores T Cell Homeostasis and Ameliorates Pathogenesis of Experimental Autoimmune Encephalomyelitis

Maintaining a constant number and ratio of immune cells is one critical aspect of the tight regulation of immune homeostasis. Breakdown of this balance will lead to autoimmune diseases such as multiple sclerosis (MS). The antiepileptic drug valproic acid (VPA) was reported to regulate the growth, su...

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Detalles Bibliográficos
Autores principales: Lv, Jie, Du, Changsheng, Wei, Wei, Wu, Zhiying, Zhao, Guixian, Li, Zhenxin, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436564/
https://www.ncbi.nlm.nih.gov/pubmed/22733814
http://dx.doi.org/10.1074/jbc.M112.356584

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