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Binding of N-Acetylglucosamine (GlcNAc) β1–6-branched Oligosaccharide Acceptors to β4-Galactosyltransferase I Reveals a New Ligand Binding Mode

N-Acetyllactosamine is the most prevalent disaccharide moiety in the glycans on the surface of mammalian cells and often found as repeat units in the linear and branched polylactosamines, known as i- and I-antigen, respectively. The β1–4-galactosyltransferase-I (β4Gal-T1) enzyme is responsible for t...

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Detalles Bibliográficos
Autores principales:	Ramakrishnan, Boopathy, Boeggeman, Elizabeth, Qasba, Pradman K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436570/ https://www.ncbi.nlm.nih.gov/pubmed/22740701 http://dx.doi.org/10.1074/jbc.M112.373514

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