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Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

BACKGROUND: Understanding the information-processing capabilities of signal transduction networks, how those networks are disrupted in disease, and rationally designing therapies to manipulate diseased states require systematic and accurate reconstruction of network topology. Data on networks centra...

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Detalles Bibliográficos
Autores principales: Kirouac, Daniel C, Saez-Rodriguez, Julio, Swantek, Jennifer, Burke, John M, Lauffenburger, Douglas A, Sorger, Peter K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436686/
https://www.ncbi.nlm.nih.gov/pubmed/22548703
http://dx.doi.org/10.1186/1752-0509-6-29