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Integrating literature-constrained and data-driven inference of signalling networks
Motivation: Recent developments in experimental methods facilitate increasingly larger signal transduction datasets. Two main approaches can be taken to derive a mathematical model from these data: training a network (obtained, e.g., from literature) to the data, or inferring the network from the da...
Autores principales: | Eduati, Federica, De Las Rivas, Javier, Di Camillo, Barbara, Toffolo, Gianna, Saez-Rodriguez, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436796/ https://www.ncbi.nlm.nih.gov/pubmed/22734019 http://dx.doi.org/10.1093/bioinformatics/bts363 |
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