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Identifying functional modules in interaction networks through overlapping Markov clustering

Motivation: In recent years, Markov clustering (MCL) has emerged as an effective algorithm for clustering biological networks—for instance clustering protein–protein interaction (PPI) networks to identify functional modules. However, a limitation of MCL and its variants (e.g. regularized MCL) is tha...

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Detalles Bibliográficos
Autores principales: Shih, Yu-Keng, Parthasarathy, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436797/
https://www.ncbi.nlm.nih.gov/pubmed/22962469
http://dx.doi.org/10.1093/bioinformatics/bts370