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Indel-tolerant read mapping with trinucleotide frequencies using cache-oblivious kd-trees

Motivation: Mapping billions of reads from next generation sequencing experiments to reference genomes is a crucial task, which can require hundreds of hours of running time on a single CPU even for the fastest known implementations. Traditional approaches have difficulties dealing with matches of l...

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Detalles Bibliográficos
Autores principales: Mahmud, Md Pavel, Wiedenhoeft, John, Schliep, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436807/
https://www.ncbi.nlm.nih.gov/pubmed/22962448
http://dx.doi.org/10.1093/bioinformatics/bts380