Identification of chemogenomic features from drug–target interaction networks using interpretable classifiers

Motivation: Drug effects are mainly caused by the interactions between drug molecules and their target proteins including primary targets and off-targets. Identification of the molecular mechanisms behind overall drug–target interactions is crucial in the drug design process. Results: We develop a c...

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Detalles Bibliográficos
Autores principales: Tabei, Yasuo, Pauwels, Edouard, Stoven, Véronique, Takemoto, Kazuhiro, Yamanishi, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436839/
https://www.ncbi.nlm.nih.gov/pubmed/22962471
http://dx.doi.org/10.1093/bioinformatics/bts412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436839/
https://www.ncbi.nlm.nih.gov/pubmed/22962471
http://dx.doi.org/10.1093/bioinformatics/bts412

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