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Identification of chemogenomic features from drug–target interaction networks using interpretable classifiers
Motivation: Drug effects are mainly caused by the interactions between drug molecules and their target proteins including primary targets and off-targets. Identification of the molecular mechanisms behind overall drug–target interactions is crucial in the drug design process. Results: We develop a c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436839/ https://www.ncbi.nlm.nih.gov/pubmed/22962471 http://dx.doi.org/10.1093/bioinformatics/bts412 |