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Re-Expression of IGF-II Is Important for Beta Cell Regeneration in Adult Mice

BACKGROUND: The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the adult is not known. In this study we investig...

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Detalles Bibliográficos
Autores principales:	Zhou, Luxian, Pelengaris, Stella, Abouna, Sylvie, Young, James, Epstein, David, Herold, Julia, Nattkemper, Tim Wilhelm, Nakhai, Hassan, Khan, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436856/ https://www.ncbi.nlm.nih.gov/pubmed/22970135 http://dx.doi.org/10.1371/journal.pone.0043623

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