Oncogenic microRNA 17-92 cluster is regulated by epithelial cell adhesion molecule and could be a potential therapeutic target in retinoblastoma

PURPOSE: Several miRNAs have been reported as candidate oncogenes and tumor suppressors, which are involved in the pathways specifically altered during tumorigenesis or metastasis. The miR 17–92 cluster located in 13q31 locus might contribute to retinoblastoma (RB) oncogenesis as 13q31 is amplified...

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Detalles Bibliográficos
Autores principales: Kandalam, Moutushy Mitra, Beta, Madhu, Maheswari, Uma K., Swaminathan, S., Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436882/
https://www.ncbi.nlm.nih.gov/pubmed/22969266

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