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Doxorubicin and NRG-1/erbB4-Deficiency Affect Gene Expression Profile: Involving Protein Homeostasis in Mouse

The accumulating evidence demonstrates the essential role of neuregulin-1 signaling in the adult heart, and, moreover, indicates that an impaired neuregulin signaling exacerbates the doxorubicin-mediated cardiac toxicity. Despite this strong data, the specific cardiomyocyte targets of the active erb...

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Detalles Bibliográficos
Autores principales: Vasti, Cecilia, Witt, Henning, Said, Matilde, Sorroche, Patricia, García-Rivello, Hernán, Ruiz-Noppinger, Patricia, Hertig, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437290/
https://www.ncbi.nlm.nih.gov/pubmed/22970387
http://dx.doi.org/10.5402/2012/745185