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Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437310/ https://www.ncbi.nlm.nih.gov/pubmed/22969832 http://dx.doi.org/10.1155/2012/948375 |
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author | Sheikh, Saba Srivastava, Ashok Tripathi, Rajesh Tripathi, Shalini Trivedi, V. P. Saxena, R. C. |
author_facet | Sheikh, Saba Srivastava, Ashok Tripathi, Rajesh Tripathi, Shalini Trivedi, V. P. Saxena, R. C. |
author_sort | Sheikh, Saba |
collection | PubMed |
description | Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral preparation, Las01 prepared absolutely as per the instruction given in the ancient Ayurvedic literature has been found to be effective as a potent anticancer drug in the human cell lines, the MCF-7 and Hela cancer cell lines. This novel preparation of Las01 is also found to be devoid of toxicity both in animals as well as in human subjects, which is the main drawback of chemotherapeutic agents used in modern system of medicine. Our results warrant multicentric clinical trials on a large scale which seems to be a future promising drug to cure incurables cancer patients. |
format | Online Article Text |
id | pubmed-3437310 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34373102012-09-11 Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals Sheikh, Saba Srivastava, Ashok Tripathi, Rajesh Tripathi, Shalini Trivedi, V. P. Saxena, R. C. Evid Based Complement Alternat Med Research Article Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral preparation, Las01 prepared absolutely as per the instruction given in the ancient Ayurvedic literature has been found to be effective as a potent anticancer drug in the human cell lines, the MCF-7 and Hela cancer cell lines. This novel preparation of Las01 is also found to be devoid of toxicity both in animals as well as in human subjects, which is the main drawback of chemotherapeutic agents used in modern system of medicine. Our results warrant multicentric clinical trials on a large scale which seems to be a future promising drug to cure incurables cancer patients. Hindawi Publishing Corporation 2012 2012-08-30 /pmc/articles/PMC3437310/ /pubmed/22969832 http://dx.doi.org/10.1155/2012/948375 Text en Copyright © 2012 Saba Sheikh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Sheikh, Saba Srivastava, Ashok Tripathi, Rajesh Tripathi, Shalini Trivedi, V. P. Saxena, R. C. Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title | Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title_full | Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title_fullStr | Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title_full_unstemmed | Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title_short | Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals |
title_sort | toxicity of a novel herbomineral preparation las01 on human cancer cell lines and its safety profile in humans and animals |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437310/ https://www.ncbi.nlm.nih.gov/pubmed/22969832 http://dx.doi.org/10.1155/2012/948375 |
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