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Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals

Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral...

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Detalles Bibliográficos
Autores principales: Sheikh, Saba, Srivastava, Ashok, Tripathi, Rajesh, Tripathi, Shalini, Trivedi, V. P., Saxena, R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437310/
https://www.ncbi.nlm.nih.gov/pubmed/22969832
http://dx.doi.org/10.1155/2012/948375
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author Sheikh, Saba
Srivastava, Ashok
Tripathi, Rajesh
Tripathi, Shalini
Trivedi, V. P.
Saxena, R. C.
author_facet Sheikh, Saba
Srivastava, Ashok
Tripathi, Rajesh
Tripathi, Shalini
Trivedi, V. P.
Saxena, R. C.
author_sort Sheikh, Saba
collection PubMed
description Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral preparation, Las01 prepared absolutely as per the instruction given in the ancient Ayurvedic literature has been found to be effective as a potent anticancer drug in the human cell lines, the MCF-7 and Hela cancer cell lines. This novel preparation of Las01 is also found to be devoid of toxicity both in animals as well as in human subjects, which is the main drawback of chemotherapeutic agents used in modern system of medicine. Our results warrant multicentric clinical trials on a large scale which seems to be a future promising drug to cure incurables cancer patients.
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spelling pubmed-34373102012-09-11 Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals Sheikh, Saba Srivastava, Ashok Tripathi, Rajesh Tripathi, Shalini Trivedi, V. P. Saxena, R. C. Evid Based Complement Alternat Med Research Article Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral preparation, Las01 prepared absolutely as per the instruction given in the ancient Ayurvedic literature has been found to be effective as a potent anticancer drug in the human cell lines, the MCF-7 and Hela cancer cell lines. This novel preparation of Las01 is also found to be devoid of toxicity both in animals as well as in human subjects, which is the main drawback of chemotherapeutic agents used in modern system of medicine. Our results warrant multicentric clinical trials on a large scale which seems to be a future promising drug to cure incurables cancer patients. Hindawi Publishing Corporation 2012 2012-08-30 /pmc/articles/PMC3437310/ /pubmed/22969832 http://dx.doi.org/10.1155/2012/948375 Text en Copyright © 2012 Saba Sheikh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sheikh, Saba
Srivastava, Ashok
Tripathi, Rajesh
Tripathi, Shalini
Trivedi, V. P.
Saxena, R. C.
Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title_full Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title_fullStr Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title_full_unstemmed Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title_short Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
title_sort toxicity of a novel herbomineral preparation las01 on human cancer cell lines and its safety profile in humans and animals
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437310/
https://www.ncbi.nlm.nih.gov/pubmed/22969832
http://dx.doi.org/10.1155/2012/948375
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