NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent

The replication of tick-borne encephalitis virus (TBEV), like that of all flaviviruses, is absolutely dependent on proteolytic processing. Production of the mature proteins C and prM from their common precursor requires the activity of the viral NS2B/3 protease (NS2B/3(pro)) at the C-terminus of pro...

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Detalles Bibliográficos
Autores principales: Kurz, Martina, Stefan, Nikolas, Zhu, Junping, Skern, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437442/
https://www.ncbi.nlm.nih.gov/pubmed/22727684
http://dx.doi.org/10.1016/j.virusres.2012.06.012

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