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The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4

The NuRD (nucleosome remodeling and deacetylase) complex serves as a crucial epigenetic regulator of cell differentiation, proliferation, and hematopoietic development by coupling the deacetylation and demethylation of histones, nucleosome mobilization, and the recruitment of transcription factors....

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Detalles Bibliográficos
Autores principales: Watson, Aleksandra A., Mahajan, Pravin, Mertens, Haydyn D.T., Deery, Michael J., Zhang, Wenchao, Pham, Peter, Du, Xiuxia, Bartke, Till, Zhang, Wei, Edlich, Christian, Berridge, Georgina, Chen, Yun, Burgess-Brown, Nicola A., Kouzarides, Tony, Wiechens, Nicola, Owen-Hughes, Tom, Svergun, Dmitri I., Gileadi, Opher, Laue, Ernest D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437443/
https://www.ncbi.nlm.nih.gov/pubmed/22575888
http://dx.doi.org/10.1016/j.jmb.2012.04.031