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Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks
Alternative inclusion of exons increases the functional diversity of proteins. Among alternatively spliced exons, tissue-specific exons play a critical role in maintaining tissue identity. This raises the question of how tissue-specific protein-coding exons influence protein function. Here we invest...
Autores principales: | Buljan, Marija, Chalancon, Guilhem, Eustermann, Sebastian, Wagner, Gunter P., Fuxreiter, Monika, Bateman, Alex, Babu, M. Madan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437557/ https://www.ncbi.nlm.nih.gov/pubmed/22749400 http://dx.doi.org/10.1016/j.molcel.2012.05.039 |
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