Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream

INTRODUCTION: The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS: We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS: The clinical course and histopathological features in our...

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Detalles Bibliográficos
Autores principales: Wilk, Michael, Zelger, Bettina G., Zelger, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare Communications 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437638/
https://www.ncbi.nlm.nih.gov/pubmed/22984658
http://dx.doi.org/10.1007/s13555-011-0002-2
Descripción
Sumario:INTRODUCTION: The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS: We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS: The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ presenting as CPH. CONCLUSION: We suggest that fluorouracil cream treatment should be considered as a therapeutic option in cases of CPH.

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