Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream

INTRODUCTION: The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS: We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS: The clinical course and histopathological features in our...

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Detalles Bibliográficos
Autores principales: Wilk, Michael, Zelger, Bettina G., Zelger, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare Communications 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437638/
https://www.ncbi.nlm.nih.gov/pubmed/22984658
http://dx.doi.org/10.1007/s13555-011-0002-2
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author Wilk, Michael
Zelger, Bettina G.
Zelger, Bernhard
author_facet Wilk, Michael
Zelger, Bettina G.
Zelger, Bernhard
author_sort Wilk, Michael
collection PubMed
description INTRODUCTION: The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS: We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS: The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ presenting as CPH. CONCLUSION: We suggest that fluorouracil cream treatment should be considered as a therapeutic option in cases of CPH.
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spelling pubmed-34376382012-09-13 Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream Wilk, Michael Zelger, Bettina G. Zelger, Bernhard Dermatol Ther (Heidelb) Case Report INTRODUCTION: The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS: We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS: The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ presenting as CPH. CONCLUSION: We suggest that fluorouracil cream treatment should be considered as a therapeutic option in cases of CPH. Springer Healthcare Communications 2011-05-04 /pmc/articles/PMC3437638/ /pubmed/22984658 http://dx.doi.org/10.1007/s13555-011-0002-2 Text en © The Author(s) 2011
spellingShingle Case Report
Wilk, Michael
Zelger, Bettina G.
Zelger, Bernhard
Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title_full Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title_fullStr Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title_full_unstemmed Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title_short Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
title_sort circumscribed palmar hypokeratosis: successful treatment with fluorouracil cream
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437638/
https://www.ncbi.nlm.nih.gov/pubmed/22984658
http://dx.doi.org/10.1007/s13555-011-0002-2
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