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Erosive lichen planus of the soles: Effective response to prednisone

BACKGROUND: Erosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids. CASE REPORT: A 38-year-old woman was referred with painful and...

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Autores principales: Goucha, Samia, Khaled, Aida, Bennani, Zaineb, Rammeh, Soumeya, Zéglaoui, Faten, Zermani, Rachida, Fazaa, Bécima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare Communications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437639/
https://www.ncbi.nlm.nih.gov/pubmed/22984660
http://dx.doi.org/10.1007/s13555-011-0005-z
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author Goucha, Samia
Khaled, Aida
Bennani, Zaineb
Rammeh, Soumeya
Zéglaoui, Faten
Zermani, Rachida
Fazaa, Bécima
author_facet Goucha, Samia
Khaled, Aida
Bennani, Zaineb
Rammeh, Soumeya
Zéglaoui, Faten
Zermani, Rachida
Fazaa, Bécima
author_sort Goucha, Samia
collection PubMed
description BACKGROUND: Erosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids. CASE REPORT: A 38-year-old woman was referred with painful and disabling erosive bilateral plantar LP, which she had experienced for 6 weeks. A 1 mg/kg/day, oral prednisone therapy led to rapid improvement and complete healing within 3 weeks, with a sustained result under a low dose maintenance therapy. DISCUSSION: Ulcerative plantar LP is significantly known to be unresponsive to several topical and systemic therapies. Surgical excision and grafting is the treatment of choice. Systemic steroids are reported to have inefficient or partial results; both on cutaneous healing and on maintenance of the result. Our patient achieved complete cicatrisation with a sustained result of 3 months under a low dose of prednisone (5 mg/day).
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spelling pubmed-34376392012-09-13 Erosive lichen planus of the soles: Effective response to prednisone Goucha, Samia Khaled, Aida Bennani, Zaineb Rammeh, Soumeya Zéglaoui, Faten Zermani, Rachida Fazaa, Bécima Dermatol Ther (Heidelb) Case Report BACKGROUND: Erosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids. CASE REPORT: A 38-year-old woman was referred with painful and disabling erosive bilateral plantar LP, which she had experienced for 6 weeks. A 1 mg/kg/day, oral prednisone therapy led to rapid improvement and complete healing within 3 weeks, with a sustained result under a low dose maintenance therapy. DISCUSSION: Ulcerative plantar LP is significantly known to be unresponsive to several topical and systemic therapies. Surgical excision and grafting is the treatment of choice. Systemic steroids are reported to have inefficient or partial results; both on cutaneous healing and on maintenance of the result. Our patient achieved complete cicatrisation with a sustained result of 3 months under a low dose of prednisone (5 mg/day). Springer Healthcare Communications 2011-08-22 /pmc/articles/PMC3437639/ /pubmed/22984660 http://dx.doi.org/10.1007/s13555-011-0005-z Text en © Springer Healthcare 2011 https://creativecommons.org/licenses/by-nc/4.0/ Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits and noncommercial use, distribution, and reproduction in any medium, provided the original authors(s) and source are credited.
spellingShingle Case Report
Goucha, Samia
Khaled, Aida
Bennani, Zaineb
Rammeh, Soumeya
Zéglaoui, Faten
Zermani, Rachida
Fazaa, Bécima
Erosive lichen planus of the soles: Effective response to prednisone
title Erosive lichen planus of the soles: Effective response to prednisone
title_full Erosive lichen planus of the soles: Effective response to prednisone
title_fullStr Erosive lichen planus of the soles: Effective response to prednisone
title_full_unstemmed Erosive lichen planus of the soles: Effective response to prednisone
title_short Erosive lichen planus of the soles: Effective response to prednisone
title_sort erosive lichen planus of the soles: effective response to prednisone
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437639/
https://www.ncbi.nlm.nih.gov/pubmed/22984660
http://dx.doi.org/10.1007/s13555-011-0005-z
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