OnabotulinumtoxinA in the treatment of neurogenic bladder

This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since its first use in 1988 to treat detrusor sphincter dyssynergia, use of botulinum toxin has increased in this group of patients. We discuss the mechanism of action, pat...

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Detalles Bibliográficos
Autores principales: Gulamhusein, Aziz, Mangera, Altaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437740/
https://www.ncbi.nlm.nih.gov/pubmed/22977301
http://dx.doi.org/10.2147/BTT.S30180
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author Gulamhusein, Aziz
Mangera, Altaf
author_facet Gulamhusein, Aziz
Mangera, Altaf
author_sort Gulamhusein, Aziz
collection PubMed
description This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since its first use in 1988 to treat detrusor sphincter dyssynergia, use of botulinum toxin has increased in this group of patients. We discuss the mechanism of action, patient selection, dosing, efficacy, and side effect profile of this now licensed treatment option.
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spelling pubmed-34377402012-09-13 OnabotulinumtoxinA in the treatment of neurogenic bladder Gulamhusein, Aziz Mangera, Altaf Biologics Review This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since its first use in 1988 to treat detrusor sphincter dyssynergia, use of botulinum toxin has increased in this group of patients. We discuss the mechanism of action, patient selection, dosing, efficacy, and side effect profile of this now licensed treatment option. Dove Medical Press 2012 2012-08-28 /pmc/articles/PMC3437740/ /pubmed/22977301 http://dx.doi.org/10.2147/BTT.S30180 Text en © 2012 Gulamhusein and Mangera, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Gulamhusein, Aziz
Mangera, Altaf
OnabotulinumtoxinA in the treatment of neurogenic bladder
title OnabotulinumtoxinA in the treatment of neurogenic bladder
title_full OnabotulinumtoxinA in the treatment of neurogenic bladder
title_fullStr OnabotulinumtoxinA in the treatment of neurogenic bladder
title_full_unstemmed OnabotulinumtoxinA in the treatment of neurogenic bladder
title_short OnabotulinumtoxinA in the treatment of neurogenic bladder
title_sort onabotulinumtoxina in the treatment of neurogenic bladder
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437740/
https://www.ncbi.nlm.nih.gov/pubmed/22977301
http://dx.doi.org/10.2147/BTT.S30180
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