Cargando…

Expression of Bim, Noxa, and Puma in non-small cell lung cancer

BACKGROUND: The BH3-only members of the Bcl-2 protein family have been proposed to play a key role in the control of apoptosis and in the initiation of the apoptotic pathways. In this study, we evaluated the expression of Bim, Noxa, and Puma in non-small cell lung cancer (NSCLC). METHODS: A total of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sakakibara-Konishi, Jun, Oizumi, Satoshi, Kikuchi, Junko, Kikuchi, Eiki, Mizugaki, Hidenori, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Nishimura, Masaharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438016/ https://www.ncbi.nlm.nih.gov/pubmed/22788963 http://dx.doi.org/10.1186/1471-2407-12-286

Ejemplares similares

Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non‐small‐cell lung cancer cells
por: Takashina, Taichi, et al.
Publicado: (2016)

Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma
por: Kikuchi, Hajime, et al.
Publicado: (2018)

DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail
por: Furuta, Megumi, et al.
Publicado: (2019)

Successful Application of Edoxaban in the Treatment of Venous Thromboembolism Recurrence in a Patient with Non-small Cell Lung Cancer after Tumor Shrinkage
por: Shoji, Tetsuaki, et al.
Publicado: (2018)

Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells
por: Kikuchi, J, et al.
Publicado: (2008)

γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer
por: Mizugaki, H, et al.
Publicado: (2012)

Roscovitine-induced Apoptosis in Neutrophils and Neutrophil Progenitors Is Regulated by the Bcl-2-Family Members Bim, Puma, Noxa and Mcl-1
por: Gautam, Sanjivan, et al.
Publicado: (2013)

Bim, Puma and Noxa upregulation by Naftopidil sensitizes ovarian cancer to the BH3-mimetic ABT-737 and the MEK inhibitor Trametinib
por: Florent, Romane, et al.
Publicado: (2020)

Correction: Roscovitine-induced Apoptosis in Neutrophils and Neutrophil Progenitors Is Regulated by the Bcl-2-Family Members Bim, Puma, Noxa and Mcl-1
por: Gautam, Sanjivan, et al.
Publicado: (2014)

Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer
por: Yokouchi, Hiroshi, et al.
Publicado: (2007)

Expression of Notch1 and Numb in small cell lung cancer
por: Kikuchi, Hajime, et al.
Publicado: (2017)

Nivolumab-induced immune thrombocytopenia in a patient with malignant pleural mesothelioma
por: Sakakibara-Konishi, Jun, et al.
Publicado: (2020)

Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant
por: Shimizu, Y, et al.
Publicado: (2008)

BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
por: Roufayel, Rabih, et al.
Publicado: (2022)

BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis
por: Delannoy, Aurélie, et al.
Publicado: (2018)

Low expression levels of microRNA-124-5p correlated with poor prognosis in colorectal cancer via targeting of SMC4
por: Jinushi, Takafumi, et al.
Publicado: (2014)

Crystalline silica-exposed human lung epithelial cells presented enhanced anchorage-independent growth with upregulated expression of BRD4 and EZH2 in autocrine and paracrine manners
por: Katabami, Motoo, et al.
Publicado: (2023)

The NOXA–MCL1–BIM axis defines lifespan on extended mitotic arrest
por: Haschka, Manuel D., et al.
Publicado: (2015)

A case of radio-insensitive SMARCA4-deficient thoracic undifferentiated carcinoma with severe right heart failure
por: Ito, Shotaro, et al.
Publicado: (2021)

Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival
por: Yokouchi, Hiroshi, et al.
Publicado: (2020)

Notch pathway regulates osimertinib drug‐tolerant persistence in EGFR ‐mutated non–small‐cell lung cancer
por: Takahashi, Hirofumi, et al.
Publicado: (2022)

Bax/Bak activation in the absence of Bid, Bim, Puma, and p53
por: Zhang, J, et al.
Publicado: (2016)

Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis
por: Wang, Jun, et al.
Publicado: (2021)

Prognostic significance of OX40(+) lymphocytes in tumor stroma of surgically resected small-cell lung cancer
por: Yokouchi, Hiroshi, et al.
Publicado: (2021)

Role of targeted therapy in metastatic colorectal cancer
por: Ohhara, Yoshihito, et al.
Publicado: (2016)

EGFR inhibition in EGFR‐mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironment
por: Shiiya, Akihiko, et al.
Publicado: (2022)

BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis
por: Holzerland, Julia, et al.
Publicado: (2020)

Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells
por: Kutuk, Ozgur, et al.
Publicado: (2010)

PUMA and NOXA Expression in Tumor-Associated Benign Prostatic Epithelial Cells Are Predictive of Prostate Cancer Biochemical Recurrence
por: Clairefond, Sylvie, et al.
Publicado: (2020)

Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker
por: Yokouchi, Hiroshi, et al.
Publicado: (2016)

A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
por: Moncunill-Massaguer, Cristina, et al.
Publicado: (2015)

Evidence against upstream regulation of the unfolded protein response (UPR) by pro-apoptotic BIM and PUMA
por: Herold, M J, et al.
Publicado: (2014)

Autophagy-dependent regulation of tumor metastasis by myeloid cells
por: Jinushi, Masahisa, et al.
Publicado: (2017)

Risk of bleeding associated with transbronchial biopsy using flexible bronchoscopy in patients with echocardiographic or chest CT evidence of pulmonary hypertension
por: Takashima, Yuta, et al.
Publicado: (2022)

A Case of High-Grade Neuroendocrine Carcinoma That Improved with Bevacizumab plus Modified FOLFOX6 as the Fourth-Line Chemotherapy
por: Takeuchi, Satoshi, et al.
Publicado: (2011)

Noxa and Puma genes regulated by hTERT promoter can mitigate growth and induce apoptosis in hepatocellular carcinoma mouse model
por: Zhao, Tongjian, et al.
Publicado: (2022)

Role of BH3-Only Molecules Bim and Puma in β-Cell Death in Pdx1 Deficiency
por: Ren, Decheng, et al.
Publicado: (2014)

Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation
por: Brockmann, A, et al.
Publicado: (2015)

Celastrol Inhibited Human Esophageal Cancer by Activating DR5-Dependent Extrinsic and Noxa/Bim-Dependent Intrinsic Apoptosis
por: Chen, Xihui, et al.
Publicado: (2022)

First-line osimertinib in elderly patients with epidermal growth factor receptor-mutated advanced non-small cell lung cancer: a retrospective multicenter study (HOT2002)
por: Yamamoto, Gaku, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2gfj7g30273bp3092gqrgm5fhh