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Nontranscriptional activation of PI3K/Akt signaling mediates hypotensive effect following activation of estrogen receptor β in the rostral ventrolateral medulla of rats
BACKGROUND: Estrogen acts on the rostral ventrolateral medulla (RVLM), where sympathetic premotor neurons are located, to elicit vasodepressor effects via an estrogen receptor (ER)β-dependent mechanism. We investigated in the present study nontranscriptional mechanism on cardiovascular effects follo...
Autores principales: | Wu, Kay LH, Chen, Chen-Hsiu, Shih, Cheng-Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438069/ https://www.ncbi.nlm.nih.gov/pubmed/22897791 http://dx.doi.org/10.1186/1423-0127-19-76 |
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