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Nontranscriptional activation of PI3K/Akt signaling mediates hypotensive effect following activation of estrogen receptor β in the rostral ventrolateral medulla of rats

BACKGROUND: Estrogen acts on the rostral ventrolateral medulla (RVLM), where sympathetic premotor neurons are located, to elicit vasodepressor effects via an estrogen receptor (ER)β-dependent mechanism. We investigated in the present study nontranscriptional mechanism on cardiovascular effects follo...

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Detalles Bibliográficos
Autores principales: Wu, Kay LH, Chen, Chen-Hsiu, Shih, Cheng-Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438069/
https://www.ncbi.nlm.nih.gov/pubmed/22897791
http://dx.doi.org/10.1186/1423-0127-19-76

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