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Isolated endogenous Nocardia endophthalmitis after immunosuppression

PURPOSE: This study is aimed to report a case of endogenous Nocardia endophthalmitis in the setting of immunosuppression from chronic steroid use. METHODS: A case report was conducted. RESULTS: A 79-year-old woman presented with decreased vision with floaters in the left eye. Ophthalmic examination...

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Autores principales: Chen, Lisa Y., Kesen, Muge R., Ghafourian, Abdalhossein, Nguyen, Quan D., Eberhart, Charles G., Do, Diana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438302/
https://www.ncbi.nlm.nih.gov/pubmed/22278699
http://dx.doi.org/10.1007/s12348-011-0057-3
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author Chen, Lisa Y.
Kesen, Muge R.
Ghafourian, Abdalhossein
Nguyen, Quan D.
Eberhart, Charles G.
Do, Diana V.
author_facet Chen, Lisa Y.
Kesen, Muge R.
Ghafourian, Abdalhossein
Nguyen, Quan D.
Eberhart, Charles G.
Do, Diana V.
author_sort Chen, Lisa Y.
collection PubMed
description PURPOSE: This study is aimed to report a case of endogenous Nocardia endophthalmitis in the setting of immunosuppression from chronic steroid use. METHODS: A case report was conducted. RESULTS: A 79-year-old woman presented with decreased vision with floaters in the left eye. Ophthalmic examination revealed severe inflammation in the anterior chamber, vitreous opacities, and retinal detachment. Vitreous cultures grew Nocardia farcinica without any systemic foci of infection found during further workup. The patient was treated with intravitreal amikacin and oral trimethoprim-sulfamethoxazole, and her retinal detachment was later repaired in the operating room. The patient has since remained stable with no signs of retinal detachment or active infection. CONCLUSIONS: Nocardia endophthalmitis is a rare, but serious intraocular infection that should be considered in the differential diagnosis in any immunosuppressed patient, including those receiving steroids, who presents with signs of intraocular infection.
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spelling pubmed-34383022012-09-17 Isolated endogenous Nocardia endophthalmitis after immunosuppression Chen, Lisa Y. Kesen, Muge R. Ghafourian, Abdalhossein Nguyen, Quan D. Eberhart, Charles G. Do, Diana V. J Ophthalmic Inflamm Infect Brief Report PURPOSE: This study is aimed to report a case of endogenous Nocardia endophthalmitis in the setting of immunosuppression from chronic steroid use. METHODS: A case report was conducted. RESULTS: A 79-year-old woman presented with decreased vision with floaters in the left eye. Ophthalmic examination revealed severe inflammation in the anterior chamber, vitreous opacities, and retinal detachment. Vitreous cultures grew Nocardia farcinica without any systemic foci of infection found during further workup. The patient was treated with intravitreal amikacin and oral trimethoprim-sulfamethoxazole, and her retinal detachment was later repaired in the operating room. The patient has since remained stable with no signs of retinal detachment or active infection. CONCLUSIONS: Nocardia endophthalmitis is a rare, but serious intraocular infection that should be considered in the differential diagnosis in any immunosuppressed patient, including those receiving steroids, who presents with signs of intraocular infection. Springer-Verlag 2012-01-26 /pmc/articles/PMC3438302/ /pubmed/22278699 http://dx.doi.org/10.1007/s12348-011-0057-3 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Brief Report
Chen, Lisa Y.
Kesen, Muge R.
Ghafourian, Abdalhossein
Nguyen, Quan D.
Eberhart, Charles G.
Do, Diana V.
Isolated endogenous Nocardia endophthalmitis after immunosuppression
title Isolated endogenous Nocardia endophthalmitis after immunosuppression
title_full Isolated endogenous Nocardia endophthalmitis after immunosuppression
title_fullStr Isolated endogenous Nocardia endophthalmitis after immunosuppression
title_full_unstemmed Isolated endogenous Nocardia endophthalmitis after immunosuppression
title_short Isolated endogenous Nocardia endophthalmitis after immunosuppression
title_sort isolated endogenous nocardia endophthalmitis after immunosuppression
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438302/
https://www.ncbi.nlm.nih.gov/pubmed/22278699
http://dx.doi.org/10.1007/s12348-011-0057-3
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