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Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS

It is well established that common genetic variants in CFH, CD46 and the CFHRs are additional risk factors for the development of aHUS. To examine the hypothesis that common variants in other complement genes have a similar effect we genotyped 501 SNPs in 47 complement genes in 94 aHUS patients from...

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Detalles Bibliográficos
Autores principales: Ermini, Luca, Goodship, Timothy H.J., Strain, Lisa, Weale, Michael E., Sacks, Steven H., Cordell, Heather J., Fremeaux-Bacchi, Veronique, Sheerin, Neil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438446/
https://www.ncbi.nlm.nih.gov/pubmed/22153652
http://dx.doi.org/10.1016/j.molimm.2011.11.003