Cargando…
Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis
The unfolded protein response (UPR) is activated by endoplasmic reticulum stress resulting from an accumulation of unfolded or mis-folded proteins. The UPR is divided into three arms, involving the activation of ATF-6, PERK and IRE-1, that together act to restrict new protein synthesis and increase...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438469/ https://www.ncbi.nlm.nih.gov/pubmed/22124452 http://dx.doi.org/10.1038/ijo.2011.233 |