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Probing the Peripheral Site of Human Butyrylcholinesterase
[Image: see text] Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) catalyze the hydrolysis of the neurotransmitter acetylcholine and, thereby, function as coregulators of cholinergic neurotransmission. For both enzymes, hydrolysis takes place near the bottom of a 20 Å deep active site g...
Autores principales: | Macdonald, Ian R., Martin, Earl, Rosenberry, Terrone L., Darvesh, Sultan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438789/ https://www.ncbi.nlm.nih.gov/pubmed/22901043 http://dx.doi.org/10.1021/bi300955k |
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