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Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data

Many viruses, including the clinically relevant RNA viruses HIV (human immunodeficiency virus) and HCV (hepatitis C virus), exist in large populations and display high genetic heterogeneity within and between infected hosts. Assessing intra-patient viral genetic diversity is essential for understand...

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Detalles Bibliográficos
Autores principales:	Beerenwinkel, Niko, Günthard, Huldrych F., Roth, Volker, Metzner, Karin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438994/ https://www.ncbi.nlm.nih.gov/pubmed/22973268 http://dx.doi.org/10.3389/fmicb.2012.00329

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