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Mapping the stabilome: a novel computational method for classifying metabolic protein stability

BACKGROUND: The half-life of a protein is regulated by a range of system properties, including the abundance of components of the degradative machinery and protein modifiers. It is also influenced by protein-specific properties, such as a protein’s structural make-up and interaction partners. New ex...

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Detalles Bibliográficos
Autores principales: Patrick, Ralph, Cao, Kim-Anh Lê, Davis, Melissa, Kobe, Bostjan, Bodén, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439251/
https://www.ncbi.nlm.nih.gov/pubmed/22682214
http://dx.doi.org/10.1186/1752-0509-6-60