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Blockade of adenosine A(2A) receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

BACKGROUND AND PURPOSE: Blockade of adenosine A(2A) receptors (A(2A)R) affords robust neuroprotection in a number of brain conditions, although the mechanisms are still unknown. A likely candidate mechanism for this neuroprotection is the control of neuroinflammation, which contributes to the amplif...

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Detalles Bibliográficos
Autores principales:	Simões, Ana Patrícia, Duarte, João A, Agasse, Fabienne, Canas, Paula Margarida, Tomé, Angelo R, Agostinho, Paula, Cunha, Rodrigo A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439355/ https://www.ncbi.nlm.nih.gov/pubmed/22901528 http://dx.doi.org/10.1186/1742-2094-9-204

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