Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O(2) and H(2)O(2). SOD also reacts with H(2)O(2), leading to the formation of a strong copper-bound oxidant species that c...

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Detalles Bibliográficos
Autores principales: Strange, Richard W., Hough, Michael A., Antonyuk, Svetlana V., Hasnain, S. Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439438/
https://www.ncbi.nlm.nih.gov/pubmed/22984565
http://dx.doi.org/10.1371/journal.pone.0044811

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