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Oxygen Glucose Deprivation in Rat Hippocampal Slice Cultures Results in Alterations in Carnitine Homeostasis and Mitochondrial Dysfunction
Mitochondrial dysfunction characterized by depolarization of mitochondrial membranes and the initiation of mitochondrial-mediated apoptosis are pathological responses to hypoxia-ischemia (HI) in the neonatal brain. Carnitine metabolism directly supports mitochondrial metabolism by shuttling long cha...
Autores principales: | Rau, Thomas F., Lu, Qing, Sharma, Shruti, Sun, Xutong, Leary, Gregory, Beckman, Matthew L., Hou, Yali, Wainwright, Mark S., Kavanaugh, Michael, Poulsen, David J., Black, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439445/ https://www.ncbi.nlm.nih.gov/pubmed/22984394 http://dx.doi.org/10.1371/journal.pone.0040881 |
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