Targeted DNA Methylation Using an Artificially Bisected M.HhaI Fused to Zinc Fingers

Little is known about the effects of single DNA methylation events on gene transcription. The ability to direct the methylation toward a single unique site within a genome would have broad use as a tool to study the effects of specific epigenetic changes on transcription. A targeted enzyme might als...

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Detalles Bibliográficos
Autores principales: Chaikind, Brian, Kilambi, Krishna Praneeth, Gray, Jeffrey J., Ostermeier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439449/
https://www.ncbi.nlm.nih.gov/pubmed/22984575
http://dx.doi.org/10.1371/journal.pone.0044852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439449/
https://www.ncbi.nlm.nih.gov/pubmed/22984575
http://dx.doi.org/10.1371/journal.pone.0044852

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