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Clinical Bioinformatics: challenges and opportunities
BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439676/ https://www.ncbi.nlm.nih.gov/pubmed/23095472 http://dx.doi.org/10.1186/1471-2105-13-S14-S1 |
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author | Bellazzi, Riccardo Masseroli, Marco Murphy, Shawn Shabo, Amnon Romano, Paolo |
author_facet | Bellazzi, Riccardo Masseroli, Marco Murphy, Shawn Shabo, Amnon Romano, Paolo |
author_sort | Bellazzi, Riccardo |
collection | PubMed |
description | BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most relevant methods, tools and infrastructures that are nowadays available for Clinical Bioinformatics (CBI), the research field that deals with clinical applications of bioinformatics. METHODS: In this editorial, the viewpoints and opinions of three world CBI leaders, who have been invited to participate in a panel discussion of the NETTAB workshop on the next challenges and future opportunities of this field, are reported. These include the development of data warehouses and ICT infrastructures for data sharing, the definition of standards for sharing phenotypic data and the implementation of novel tools to implement efficient search computing solutions. RESULTS: Some of the most important design features of a CBI-ICT infrastructure are presented, including data warehousing, modularity and flexibility, open-source development, semantic interoperability, integrated search and retrieval of -omics information. CONCLUSIONS: Clinical Bioinformatics goals are ambitious. Many factors, including the availability of high-throughput "-omics" technologies and equipment, the widespread availability of clinical data warehouses and the noteworthy increase in data storage and computational power of the most recent ICT systems, justify research and efforts in this domain, which promises to be a crucial leveraging factor for biomedical research. |
format | Online Article Text |
id | pubmed-3439676 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34396762012-09-17 Clinical Bioinformatics: challenges and opportunities Bellazzi, Riccardo Masseroli, Marco Murphy, Shawn Shabo, Amnon Romano, Paolo BMC Bioinformatics Introduction BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most relevant methods, tools and infrastructures that are nowadays available for Clinical Bioinformatics (CBI), the research field that deals with clinical applications of bioinformatics. METHODS: In this editorial, the viewpoints and opinions of three world CBI leaders, who have been invited to participate in a panel discussion of the NETTAB workshop on the next challenges and future opportunities of this field, are reported. These include the development of data warehouses and ICT infrastructures for data sharing, the definition of standards for sharing phenotypic data and the implementation of novel tools to implement efficient search computing solutions. RESULTS: Some of the most important design features of a CBI-ICT infrastructure are presented, including data warehousing, modularity and flexibility, open-source development, semantic interoperability, integrated search and retrieval of -omics information. CONCLUSIONS: Clinical Bioinformatics goals are ambitious. Many factors, including the availability of high-throughput "-omics" technologies and equipment, the widespread availability of clinical data warehouses and the noteworthy increase in data storage and computational power of the most recent ICT systems, justify research and efforts in this domain, which promises to be a crucial leveraging factor for biomedical research. BioMed Central 2012-09-07 /pmc/articles/PMC3439676/ /pubmed/23095472 http://dx.doi.org/10.1186/1471-2105-13-S14-S1 Text en Copyright ©2012 Bellazzi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Introduction Bellazzi, Riccardo Masseroli, Marco Murphy, Shawn Shabo, Amnon Romano, Paolo Clinical Bioinformatics: challenges and opportunities |
title | Clinical Bioinformatics: challenges and opportunities |
title_full | Clinical Bioinformatics: challenges and opportunities |
title_fullStr | Clinical Bioinformatics: challenges and opportunities |
title_full_unstemmed | Clinical Bioinformatics: challenges and opportunities |
title_short | Clinical Bioinformatics: challenges and opportunities |
title_sort | clinical bioinformatics: challenges and opportunities |
topic | Introduction |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439676/ https://www.ncbi.nlm.nih.gov/pubmed/23095472 http://dx.doi.org/10.1186/1471-2105-13-S14-S1 |
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