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Clinical Bioinformatics: challenges and opportunities

BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most...

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Autores principales: Bellazzi, Riccardo, Masseroli, Marco, Murphy, Shawn, Shabo, Amnon, Romano, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439676/
https://www.ncbi.nlm.nih.gov/pubmed/23095472
http://dx.doi.org/10.1186/1471-2105-13-S14-S1
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author Bellazzi, Riccardo
Masseroli, Marco
Murphy, Shawn
Shabo, Amnon
Romano, Paolo
author_facet Bellazzi, Riccardo
Masseroli, Marco
Murphy, Shawn
Shabo, Amnon
Romano, Paolo
author_sort Bellazzi, Riccardo
collection PubMed
description BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most relevant methods, tools and infrastructures that are nowadays available for Clinical Bioinformatics (CBI), the research field that deals with clinical applications of bioinformatics. METHODS: In this editorial, the viewpoints and opinions of three world CBI leaders, who have been invited to participate in a panel discussion of the NETTAB workshop on the next challenges and future opportunities of this field, are reported. These include the development of data warehouses and ICT infrastructures for data sharing, the definition of standards for sharing phenotypic data and the implementation of novel tools to implement efficient search computing solutions. RESULTS: Some of the most important design features of a CBI-ICT infrastructure are presented, including data warehousing, modularity and flexibility, open-source development, semantic interoperability, integrated search and retrieval of -omics information. CONCLUSIONS: Clinical Bioinformatics goals are ambitious. Many factors, including the availability of high-throughput "-omics" technologies and equipment, the widespread availability of clinical data warehouses and the noteworthy increase in data storage and computational power of the most recent ICT systems, justify research and efforts in this domain, which promises to be a crucial leveraging factor for biomedical research.
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spelling pubmed-34396762012-09-17 Clinical Bioinformatics: challenges and opportunities Bellazzi, Riccardo Masseroli, Marco Murphy, Shawn Shabo, Amnon Romano, Paolo BMC Bioinformatics Introduction BACKGROUND: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, held in Pavia, Italy, in October 2011 was aimed at presenting some of the most relevant methods, tools and infrastructures that are nowadays available for Clinical Bioinformatics (CBI), the research field that deals with clinical applications of bioinformatics. METHODS: In this editorial, the viewpoints and opinions of three world CBI leaders, who have been invited to participate in a panel discussion of the NETTAB workshop on the next challenges and future opportunities of this field, are reported. These include the development of data warehouses and ICT infrastructures for data sharing, the definition of standards for sharing phenotypic data and the implementation of novel tools to implement efficient search computing solutions. RESULTS: Some of the most important design features of a CBI-ICT infrastructure are presented, including data warehousing, modularity and flexibility, open-source development, semantic interoperability, integrated search and retrieval of -omics information. CONCLUSIONS: Clinical Bioinformatics goals are ambitious. Many factors, including the availability of high-throughput "-omics" technologies and equipment, the widespread availability of clinical data warehouses and the noteworthy increase in data storage and computational power of the most recent ICT systems, justify research and efforts in this domain, which promises to be a crucial leveraging factor for biomedical research. BioMed Central 2012-09-07 /pmc/articles/PMC3439676/ /pubmed/23095472 http://dx.doi.org/10.1186/1471-2105-13-S14-S1 Text en Copyright ©2012 Bellazzi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Introduction
Bellazzi, Riccardo
Masseroli, Marco
Murphy, Shawn
Shabo, Amnon
Romano, Paolo
Clinical Bioinformatics: challenges and opportunities
title Clinical Bioinformatics: challenges and opportunities
title_full Clinical Bioinformatics: challenges and opportunities
title_fullStr Clinical Bioinformatics: challenges and opportunities
title_full_unstemmed Clinical Bioinformatics: challenges and opportunities
title_short Clinical Bioinformatics: challenges and opportunities
title_sort clinical bioinformatics: challenges and opportunities
topic Introduction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439676/
https://www.ncbi.nlm.nih.gov/pubmed/23095472
http://dx.doi.org/10.1186/1471-2105-13-S14-S1
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