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Improving ChIP-seq peak-calling for functional co-regulator binding by integrating multiple sources of biological information

BACKGROUND: Chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-seq) is increasingly being applied to study genome-wide binding sites of transcription factors. There is an increasing interest in understanding the mechanism of action of co-regulator proteins, which do not b...

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Detalles Bibliográficos
Autores principales: Osmanbeyoglu, Hatice Ulku, Hartmaier, Ryan J, Oesterreich, Steffi, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439677/
https://www.ncbi.nlm.nih.gov/pubmed/22369349
http://dx.doi.org/10.1186/1471-2164-13-S1-S1