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Imputation reliability on DNA biallelic markers for drug metabolism studies
BACKGROUND: Imputation is a statistical process used to predict genotypes of loci not directly assayed in a sample of individuals. Our goal is to measure the performance of imputation in predicting the genotype of the best known gene polymorphisms involved in drug metabolism using a common SNP array...
Autores principales: | Mijatovic, Vladan, Iacobucci, Ilaria, Sazzini, Marco, Xumerle, Luciano, Mori, Antonio, Pignatti, Pier Franco, Martinelli, Giovanni, Malerba, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439717/ https://www.ncbi.nlm.nih.gov/pubmed/23095502 http://dx.doi.org/10.1186/1471-2105-13-S14-S7 |
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