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Entorhinal theta-frequency input to the dentate gyrus trisynaptically evokes hippocampal CA1 LTP

There exists substantial evidence that some forms of explicit learning in mammals require long-term potentiation (LTP) at hippocampal CA3-CA1 synapses. While CA1 LTP has been well characterized at the monosynaptic level, it still remains unclear how the afferent systems to the hippocampus can initia...

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Detalles Bibliográficos
Autores principales: Stepan, Jens, Dine, Julien, Fenzl, Thomas, Polta, Stephanie A., von Wolff, Gregor, Wotjak, Carsten T., Eder, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439738/
https://www.ncbi.nlm.nih.gov/pubmed/22988432
http://dx.doi.org/10.3389/fncir.2012.00064