Angiosarcoma of the scalp associated with Xeroderma pigmentosum

Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneous maligna...

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Autores principales: Sharma, Shilpi, Deshmukh, Anuja D., Bal, Munita M., Chaukar, Devendra A., Dcruz, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439790/
https://www.ncbi.nlm.nih.gov/pubmed/22988356
http://dx.doi.org/10.4103/0971-5851.99753
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author Sharma, Shilpi
Deshmukh, Anuja D.
Bal, Munita M.
Chaukar, Devendra A.
Dcruz, Anil K.
author_facet Sharma, Shilpi
Deshmukh, Anuja D.
Bal, Munita M.
Chaukar, Devendra A.
Dcruz, Anil K.
author_sort Sharma, Shilpi
collection PubMed
description Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneous malignancies are common, the simultaneous occurrence of angiosarcoma and basal cell carcinoma is a rare phenomenon. We report a case of a 25-year-old male with XP with angiosarcoma scalp and basal cell carcinoma of face and occiput and discuss the treatment of this aggressive neoplasm with a review of the literature pertaining to it.
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spelling pubmed-34397902012-09-17 Angiosarcoma of the scalp associated with Xeroderma pigmentosum Sharma, Shilpi Deshmukh, Anuja D. Bal, Munita M. Chaukar, Devendra A. Dcruz, Anil K. Indian J Med Paediatr Oncol Case Report Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneous malignancies are common, the simultaneous occurrence of angiosarcoma and basal cell carcinoma is a rare phenomenon. We report a case of a 25-year-old male with XP with angiosarcoma scalp and basal cell carcinoma of face and occiput and discuss the treatment of this aggressive neoplasm with a review of the literature pertaining to it. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3439790/ /pubmed/22988356 http://dx.doi.org/10.4103/0971-5851.99753 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sharma, Shilpi
Deshmukh, Anuja D.
Bal, Munita M.
Chaukar, Devendra A.
Dcruz, Anil K.
Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title_full Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title_fullStr Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title_full_unstemmed Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title_short Angiosarcoma of the scalp associated with Xeroderma pigmentosum
title_sort angiosarcoma of the scalp associated with xeroderma pigmentosum
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439790/
https://www.ncbi.nlm.nih.gov/pubmed/22988356
http://dx.doi.org/10.4103/0971-5851.99753
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