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The Non-Coding Oncogene: A Case of Missing DNA Evidence?
The evidence that links classical protein-coding proto-oncogenes and tumor suppressors, such as MYC, RAS, P53, and RB, to carcinogenesis is indisputable. Multiple lines of proof show how random somatic genomic alteration of such genes (e.g., mutation, deletion, or amplification), followed by selecti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439828/ https://www.ncbi.nlm.nih.gov/pubmed/22988449 http://dx.doi.org/10.3389/fgene.2012.00170 |